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. 2022 Jul 6;20:303. doi: 10.1186/s12967-022-03503-7

Fig. 1.

Fig. 1

eIF6 is upregulated in ESCA tumor tissues and correlates with the prognosis of ESCA patients. A Expression patterns of human eIF6 mRNA across multiple types of tumor tissues and normal tissues. B eIF6 mRNA expression levels in EA (n = 80), ESCC tumor tissues (n = 82), and normal tissues (n = 11) from the TCGA-ESCA cohort. C The expression level of eIF6 was determined by qRT-PCR and Western blotting (D) in 13 paired ESCC tissues and adjacent tissues. T, ESCA tissues; N, paired adjacent normal tissues. E Representative IHC images and scores F of eIF6 in adjacent normal tissues and ESCC tissues (normal = 38, tumor = 52). G ROC curve showing the diagnostic value of eIF6 patients with ESCA (n = 162). H Kaplan–Meier curves showing the OS in EA and ESCC I patients based on the eIF6 mRNA expression level. *p < 0.05, **p < 0.01, ***p < 0.001