Table 3.

Correlation analysis between eIF6 and relate genes and markers of innate immunity cells in ESCA

Description	Genemarkers	TIMER (n = 184)				GEPIA2 (n = 181)
		Purity		None
		Cor	p	Cor	p	Cor	p
Monocyte	CD14	− 0.154	*	− 0.132	0.073	− 0.094	0.210
	CD86	− 0.286	*	− 0.262	*	− 0.230	*
	CD16 (FCGR3A)	− 0.238	*	− 0.223	*	− 0.190	*
TAM	CD68	0.139	0.062	0.156	*	0.140	0.061
	CCL2	− 0.266	*	− 0.262	*	− 0.130	0.077
	CCL5	− 0.117	0.116	− 0.125	0.090	− 0.081	0.280
M1 Macrophage	INOS (NOS2)	0.137	0.066	0.129	0.080	0.160	*
	CXCL10	− 0.129	0.083	− 0.121	0.101	− 0.018	0.800
	TNF-α (TNF)	− 0.029	0.695	− 0.008	0.913	− 0.028	0.710
M2 Macrophage	CD206 (MRC1)	− 0.203	*	− 0.200	*	− 0.150	*
	CD163	− 0.208	*	− 0.199	*	− 0.094	0.210
	IL10	− 0.177	*	− 0.182	*	− 0.150	*
Neutrophils	CD66b (CEACAM8)	0.142	0.057	0.113	0.127	0.001	0.980
	CD11b (ITGAM)	− 0.189	*	− 0.166	*	− 0.170	*
	CCR7	− 0.039	0.601	− 0.059	0.427	− 0.180	*
	CD15 (FUT4)	0.085	0.256	0.071	0.340	0.110	0.160
Natural killer cell	KIR2DL1	0.052	0.486	0.041	0.584	− 0.090	0.230
	KIR2DL3	− 0.167	*	− 0.159	*	− 0.091	0.220
	KIR2DL4	0.037	0.625	0.035	0.633	− 0.025	0.740
	KIR3DL1	0.022	0.766	0.013	0.858	− 0.095	0.200
	KIR3DL2	− 0.107	0.153	− 0.107	0.147	− 0.029	0.700
	KIR3DL3	− 0.001	0.993	0.003	0.963	− 0.048	0.520
	KIR2DS4	0.041	0.586	0.053	0.470	− 0.095	0.200
Dendritic cell	HLA-DPB1	− 0.163	*	− 0.165	*	− 0.210	*
	HLA-DQB1	− 0.078	0.294	− 0.093	0.210	− 0.096	0.200
	HLA-DRA	− 0.129	0.083	− 0.136	0.065	− 0.110	0.130
	HLA-DPA1	− 0.137	0.065	− 0.138	0.061	− 0.130	0.070
	BDCA-1 (CD1C)	− 0.250	*	− 0.249	*	− 0.250	*
	BDCA-4 (NRP1)	− 0.213	*	− 0.215	*	− 0.100	0.170
	CD11c (ITGAX)	− 0.178	*	− 0.168	*	− 0.210	*
	NKp46 (NCR1)	− 0.031	0.681	− 0.045	0.547	− 0.100	0.170

TAM, tumor associated macrophage; Cor, R value of Spearman’s correlation. Purity, correlation adjusted by purity. *p < 0.05. None, correlation without adjustment