Table 2.
Brain measures | Model 1 | Model 2 | ||||||
---|---|---|---|---|---|---|---|---|
ß | SD | t-statistic | p value | ß | SD | t-statistic | p value | |
Total brain volume | − 0.06 | 0.88 | − 3.16 | 0.002* | − 0.03 | 0.88 | − 1.69 | 0.089 |
Cortical gray matter volume | − 0.06 | 0.88 | − 3.17 | 0.001* | − 0.03 | 0.88 | − 1.46 | 0.144 |
Subcortical gray matter volume | − 0.06 | 0.88 | − 2.79 | 0.005* | − 0.04 | 0.88 | − 1.77 | 0.075 |
Cerebral white matter volume | − 0.04 | 0.88 | − 2.09 | 0.036 | − 0.02 | 0.88 | − 1.12 | 0.256 |
CSF volume | − 0.01 | 0.88 | − 0.61 | 0.540 | 0.01 | 0.88 | 0.54 | 0.592 |
Cerebellum cortex volume | − 0.08 | 0.88 | − 4.15 | 3.39·10–5* | − 0.06 | 0.88 | − 2.84 | 0.004* |
Cerebellum white matter volume | − 0.06 | 0.88 | − 2.92 | 0.003* | − 0.05 | 0.88 | − 2.34 | 0.019 |
Mean amygdala volume (L + R) | − 0.05 | 0.88 | − 2.39 | 0.017 | − 0.02 | 0.88 | − 0.96 | 0.339 |
Mean gyrification | − 0.09 | 0.88 | − 4.24 | 2.25·10–5* | − 0.06 | 0.88 | − 2.81 | 0.005* |
Mean surface area | − 0.09 | 0.88 | − 4.73 | 2.44·10–6* | − 0.06 | 0.88 | − 3.12 | 0.002* |
Mean cortical thickness | 0.03 | 0.88 | 1.47 | 0.142 | 0.05 | 0.88 | 2.38 | 0.018 |
aModel 1 is adjusted for sex, age at SRS and the difference in age between SRS and MRI; Model 2 is additionally adjusted for child ethnicity, maternal education, maternal smoking and drinking during pregnancy. The effects are standardized
*Significant after Bonferroni correction (p < 0.005)