Table 1.
Demographics of subjects
|
Variables
|
ALL (n = 437)
|
Fatty liver (n = 110)
|
Non-fatty liver (n = 327)
|
P
value
|
| Gender (Male/Female) | 269/168 | 80/30 | 189/138 | 0.005 |
| Age (yr) | 74.0 ± 13.0 | 64.7 ± 13.0 | 77.1 ± 11.0 | < 0.001 |
| Height (cm) | 159.4 ± 10.2 | 163.2 ± 10.0 | 158.2 ± 9.9 | < 0.001 |
| Body weight (kg) | 61.3 ± 14.5 | 70.0 ± 16.6 | 58.5 ± 12.5 | < 0.001 |
| BMI (kg/m2) | 24.0 ± 4.9 | 26.0 ± 4.7 | 23.3 ± 4.7 | < 0.001 |
| HbA1c (%) | 7.0 ± 1.2 | 7.2 ± 1.2 | 6.9 ± 1.2 | 0.066 |
| Blood glucose (mg/dl) | 164 ± 80 | 170 ± 116 | 161 ± 63 | 0.297 |
| White blood cells (/μL) | 6618 ± 2299 | 7056 ± 1649 | 6470 ± 2463 | 0.021 |
| Hemoglobin (g/dL) | 12.6 ± 2.4 | 14.2 ± 2.1 | 12.0 ± 2.2 | < 0.001 |
| Platelets (104/μL) | 20.7 ± 7.0 | 20.4 ± 5.5 | 20.8 ± 7.4 | 0.615 |
| Prothrombin time (%) | 89.6 ± 22.3 | 89.2 ± 23.6 | 89.7 ± 22.1 | 0.895 |
| Albumin (g/dL) | 3.7 ± 0.7 | 3.9 ± 0.6 | 3.6 ± 0.6 | < 0.001 |
| Total bilirubin (mg/dL) | 0.76 ± 0.50 | 0.86 ± 0.49 | 0.72 ± 0.49 | 0.015 |
| ALP (U/L) | 266 ± 156 | 247 ± 80 | 272 ± 176 | 0.182 |
| AST (U/L) | 25.3 ± 22.8 | 29.0 ± 20.2 | 23.0 ± 23.4 | 0.014 |
| ALT (U/L) | 23.5 ± 20.8 | 35.0 ± 27.4 | 19.0 ± 16.1 | < 0.001 |
| GGT (U/L) | 46.2 ± 63.1 | 68.0 ± 74.4 | 38.0 ± 56.6 | < 0.001 |
| Creatinine (mg/dL) | 1.71 ± 2.10 | 1.27 ± 1.58 | 1.85 ± 2.22 | 0.012 |
| eGFR (mL/min) | 52.0 ± 29.2 | 58.9 ± 21.9 | 49.6 ± 30.9 | 0.004 |
| Total cholesterol (mg/dL) | 181 ± 50 | 193 ± 64 | 177 ± 43 | 0.012 |
| HDL cholesterol (mg/dL) | 53 ± 17 | 50 ± 15 | 54 ± 17 | 0.039 |
| Triglyceride (mg/dL) | 160 ± 179 | 228 ± 299 | 134 ± 87 | < 0.001 |
| LDL cholesterol (mg/dL) | 101 ± 36 | 111 ± 40 | 96 ± 33 | 0.001 |
| FIB-4 index | 2.20 ± 1.56 | 1.84 ± 1.08 | 2.32 ± 1.67 | 0.005 |
| Cirrhosis (%) | 8 (1.8) | 1 (0.9) | 7 (2.1) | 0.405 |
| Hepatocellular carcinoma (%) | 7 (1.6) | 1 (0.9) | 6 (1.8) | 0.504 |
| Cerebrovascular accident (%) | 45 (10) | 9 (8.2) | 36 (11) | 0.399 |
| Cardiovasculart disease (%) | 137 (31) | 29 (26) | 108 (33) | 0.193 |
| Dyslipidemia (%) | 205 (47) | 53 (48) | 152 (46) | 0.758 |
| Hypertension (%) | 270 (62) | 57 (51) | 213 (65) | 0.013 |
| Dialysis (%) | 45 (10) | 3 (2.7) | 42 (12) | 0.003 |
Values are expessed as mean ± SD. Statistical analysis are conducted using the chi-squared test, Fisher’s exact test, or Student’s t test. ALP: Alkaline phosphatase; AST: Aspartate aminotransferase; ALT: Alanin aminotransferase; BMI: Body mass index; GGT: Gamma glutamyl transpeptidase; eGFR: Estimated glomelular filtration rate; HDL cholesterol: High density lipoprotein cholesterol; LDL cholesterol: Low density lipoprotein cholesterol; FIB-4 index: Fibrosis-4 index.