Table 4.
|
During biliary obstruction (n = 55)
|
48 h after drainage (n = 55)
|
28 d after drainage (n = 55)
|
P
value1
|
Bilirubin (mmol/L) | 145 (63.9-230.7) | 88.5 (38.75-190.5) | 25 (18.85-38.7) | < 0.001 |
ALT (U/L) | 133 (78-194) | 91.5 (63.75-144.25) | 30 (23-46.5) | < 0.001 |
GGT (U/L) | 278 (103-421) | 194 (103.25-267.25) | 36 (28-64) | < 0.001 |
ALP (U/L) | 448 (288.5-612.5) | 382.5 (184-606.5) | 85 (61-111) | < 0.001 |
AST (U/L) | 284 (260.5-382) | 281.5 (231.75-429.25) | 123 (103.5-166) | < 0.001 |
CRP (mg/L) | 10.0 (5.8-14.1) | 17.9 (5.9-26.8) | 8.3 (2.5-17.3) | 0.009 |
IL-6 (pg/mL) | 9 (6-13) | 11 (7-22) | 9 (5-21.5) | 0.332 |
TNF-α (pg/mL) | 11 (8.5-13) | 10 (9-12) | 10 (8-12.5) | 0.088 |
Ghrelin (pg/mL) | 1549 (1079.5-2400.5) | 1648.5 (1137.25-2767) | 1612 (891.5-2962) | 0.552 |
Cholecystokinin (pg/mL) | 213.0 (161.0-380.7) | 266.0 (203.0-400.5) | 235.0 (158.0-433.0) | 0.03 |
Albumin (g/L) | 37.1 (33.0-40.8) | 35.0 (32.4 -38.0) | 38.0 (35.0-42.0) | < 0.001 |
Appetite (VAS) | 4 (2-6) | 6 (4-8) | 7 (6-9) | < 0.001 |
BMI (kg/m2) | 24.5 (21.3-28.2) | 24.4 (20.6-27.9) | 24.9 (21.2-26.8) | < 0.001 |
Body fat (%) | 23 (17-25) | 23 (17-24) | 23 (19-25) | 0.002 |
NRS 2002 | 3.0 (2.0-4.0) | 3.5 (2.0-4.0) | 0.0 (0.0-4.0) | < 0.001 |
Friedman test across three observations.
Values are presented as median (Q1-Q3); ALT: Alanine aminotransferase; GGT: Gamma-glutamyl transferase; ALP: Alkaline phosphatase; AST: Aspartate aminotransferase; CRP: C-reactive protein; IL-6: Interleukin 6; TNF-α: Tumor necrosis factor α; VAS: Visual analog scale; BMI: Body mass index; NRS: Nutritional risk screening.