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. 2022 Jun 22;13:920065. doi: 10.3389/fimmu.2022.920065

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Copyright © 2022 Ren, Xu, Zhao, Shao, Chen, Lu and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of supplementary 1% and 2% of CLNT on intestinal microbiota in IHNV-infected rainbow trout. (A) OTU-Venn analysis of intestinal microbiota; (B) PLS-DA analysis of intestinal microbiota; (C) relative abundances of major phyla above 0.10% in at least one group; (D) community heat map analysis of top 20 genera in each group; (E) LDA Effect Size (LEfSe) analysis of microbes between NC and IH groups, LDA>4, P<0.05; (F) LEfSe analysis of microbes between LD and IH groups, LDA>2.5, P<0.05; (G) LEfSe analysis of microbes between HD and IH groups, LDA>2, P<0.05.