Table 2:
Subject ID | Diflunisal duration of treatment (years) | Reason for discontinuation |
---|---|---|
01 | 5.8 | Reduction in creatinine clearance |
02 | 0.4 | Fatigue |
03 | 1.0 | Reduction in creatinine clearance |
04 | 8.4 | Enrollment in another clinical trial |
05 | 4.8 | Reduction in creatinine clearance |
06 | 2.8 | Gastrointestinal bleeding |
07 | 5.0 | Enrollment in another clinical trial |
08 | 2.5 | Initiation of systemic anticoagulation* |
09 | 1.6 | Reduction in creatinine clearance |
10 | 0.8 | Reduction in creatinine clearance |
11 | 3.0 | Reduction in creatinine clearance |
12 | 3.0 | Reduction in creatinine clearance |
13 | 0.1 | Volume overload |
14 | 2.9 | Initiation of systemic anticoagulation* |
Diflunisal was discontinued at the discretion of the treating physician to reduce the risk of bleeding with initiation of systemic anticoagulation.