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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Amyloid. 2022 Jan 27;29(2):71–78. doi: 10.1080/13506129.2021.2000388

Table 5:

Differences between treated and untreated patients at 1 year follow up.

Untreated n = 69 Diflunisal n = 35 p value
Baseline 1 year follow up Baseline 1 year follow up
NYHA class 0.46
I 17 (24.6) 3 (4.3) 13 (37.1) 9 (25.7)
II 23 (33.3) 2 (2.9) 16 (45.7) 18 (51.4)
III 26 (37.7) 19 (27.5) 5 (14.3) 6 (17.1)
eGFR, mL/min/1.73m2 53.2 ± 17.6 51.2 ± 20.1 67.3 ± 17.4 59.1 ± 16.7 0.03
BNP, pg/mL 520.1 ± 296.1 595.8 ± 452.7 335.0 ± 365.6 300.5 ± 247.4 0.11
logBNP 6.1 ± 0.7 6.1 ± 0.7 5.5 ± 0.8 5.4 ± 0.8 0.19
Troponin I, ng/mL 0.2 ± 0.34 0.25 ± 0.6 0.1 ± 0.1 0.09 ± 0.07 0.12
LVEF, % 45.0 ± 11.5 43.7 ± 12.9 53.1 ± 12.0 54.1 ± 10.2 0.27
Interventricular septal thickness, mm 15.8 ± 2.3 16.6 ± 2.0 16.6 ± 2.7 17.2 ± 2.33 0.15
Posterior wall thickness, mm 15.8 ± 2.4 16.3 ± 1.9 16.5 ± 2.2 16.7 ± 2.1 0.04

Continuous variables expressed as mean +/− standard deviation and categorical variables as number (%). p values reflect change differences between follow-up and baseline for treated versus untreated patients. eGFR was calculated using the CKD-Epi equation.