TABLE 1.
Baseline Characteristics of Study Participants
| Variable | Entire population (n = 58) | Negative 11C-PiB PET/CT (n = 23) | Positive 11C-PiB PET/CT (n = 35) | P |
|---|---|---|---|---|
| Demographics | ||||
| Age (y) | 64.0 ± 9.1 | 61.7 ± 7.6 | 65.5 ± 9.8 | 0.121 |
| Male | 25 (43.1%) | 9 (39.1%) | 16 (45.7%) | 0.787 |
| Systolic blood pressure (mm Hg) | 109.5 (100.2–119.5) | 111.0 (104.5–122.5) | 104.0 (92.5–114.0) | 0.034 |
| Diastolic blood pressure (mm Hg) | 68.0 ± 7.5 | 68.5 ± 7.7 | 67.6 ± 7.5 | 0.663 |
| Body mass index (kg/m2) | 22.6 ± 3.1 | 23.1 ± 3.4 | 22.2 ± 3.9 | 0.270 |
| Comorbidities | ||||
| Hypertension | 13 (22.4%) | 5 (21.7%) | 8 (22.9%) | 0.999 |
| Diabetes | 13 (22.4%) | 2 (8.7%) | 11 (31.4%) | 0.087 |
| Dyslipidemia | 6 (10.3%) | 1 (4.3%) | 5 (14.3%) | 0.386 |
| End-stage renal disease | 4 (6.8%) | 2 (8.7%) | 2 (5.7%) | 0.999 |
| Atrial fibrillation | 5 (8.6%) | 4 (17.4%) | 1 (3.0%) | 0.075 |
| Chemotherapy | 51 (87.9%) | 22 (95.7%) | 29 (82.9%) | 0.224 |
| Autologous PBSCT | 10 (17.2%) | 7 (30.4%) | 3 (8.6%) | 0.040 |
| Echocardiography data | ||||
| LV end-diastolic dimension (mm) | 43.8 ± 5.2 | 45.1 ± 6.0 | 43.0 ± 4.4 | 0.134 |
| LV end-systolic dimension (mm) | 28.8 ± 5.2 | 29.2 ± 6.0 | 28.5 ± 4.7 | 0.640 |
| LV mass index (kg/m2) | 121.2 ± 34.7 | 116.8 ± 36.8 | 124.2 ± 33.5 | 0.430 |
| LV ejection fraction (%) | 56.5 (52.0–62.0) | 58.0 (51.5–66.5) | 56.0 (52.5–60.5) | 0.321 |
| LV ejection fraction < 60% | 19 (32.8%) | 10 (43.5%) | 9 (25.7%) | 0.261 |
| E velocity (m/s) | 0.85 ± 0.28 | 0.76 ± 0.23 | 0.91 ± 0.31 | 0.021 |
| e’ velocity (cm/s) | 4.1 ± 1.1 | 4.4 ± 1.0 | 3.8 ± 1.1 | 0.043 |
| E/e’ ratio | 19.9 (14.9–29.5) | 16.7 (13.4–21.0) | 22.5 (17.0–33.3) | 0.004 |
| Estimated PASP (mm Hg) | 38.0 (32.5–45.0) | 37.0 (31.5–42.5) | 40.5 (32.8–45.0) | 0.441 |
| Left atrial size (mm) | 43.3 ± 6.7 | 43.1 ± 7.2 | 43.4 ± 6.4 | 0.863 |
PBSCT = peripheral blood stem cell transplantation; LV = left ventricular; PASP = pulmonary arterial systolic pressure.
Data for continuous variables are mean ± SD or median followed by IQ. Data for categoric variables are frequencies followed by percentages. P values are for comparisons between positive and negative 11C-PiB PET/CT groups.