TABLE 4.

VLDL subfractions of young and older adults at baseline and older adults before and after 6 mo of placebo or n–3-PUFA supplementation¹

								Old n–3 PUFA vs. old placebo
			Old n–3 PUFA (n = 22)		Old placebo (n = 22)		Young vs. old	Adjusted mean
	Young (n = 30)	Old (n = 54)	Baseline	Follow-up	Baseline	Follow-up	P value	difference	95% CI	P value
Triglycerides, VLDL-1, mg/dL	33.0 ± 22.7	24.7 ± 19.4	27.4 ± 22.3	19.0 ± 9.80	22.6 ± 18.9	20.2 ± 8.86	0.079	2.42	−2.37, 7.21	0.314
Triglycerides, VLDL-2, mg/dL	8.50 ± 5.54	7.67 ± 6.69	8.04 ± 7.08	7.42 ± 3.38	7.36 ± 7.41	5.88 ± 3.24	0.564	−1.37	−3.03, 0.303	0.106
Triglycerides, VLDL-3, mg/dL	6.14 ± 4.41	6.26 ± 5.76	6.35 ± 5.49	5.23 ± 3.33	6.28 ± 6.89	4.74 ± 3.47	0.920	−0.466	−2.00, 1.07	0.543
Triglycerides, VLDL-4, mg/dL	5.86 ± 2.75	7.30 ± 3.56	7.19 ± 2.91	6.53 ± 2.91	7.57 ± 4.55	6.90 ± 3.28	0.059	0.164	−1.25, 1.58	0.816
Triglycerides, VLDL-5, mg/dL	2.95 ± 0.53	3.77 ± 0.69	3.63 ± 0.52	3.80 ± 0.61	3.97 ± 0.84	4.08 ± 0.75	<0.001	0.029	−0.234, 0.292	0.824
Cholesterol, VLDL-1, mg/dL	6.41 ± 3.74	5.60 ± 3.70	5.88 ± 4.03	3.35 ± 1.92	5.41 ± 3.71	4.98 ± 1.78	0.338	1.74	0.775, 2.71	0.001
Cholesterol, VLDL-2, mg/dL	1.85 ± 1.34	1.84 ± 1.84	1.86 ± 1.88	1.14 ± 0.80	1.85 ± 2.11	1.39 ± 1.08	0.990	0.255	−0.216, 0.726	0.280
Cholesterol, VLDL-3, mg/dL	1.81 ± 1.53	1.75 ± 2.11	1.77 ± 2.06	0.85 ± 1.13	1.77 ± 2.49	1.13 ± 1.27	0.887	0.279	−0.278, 0.836	0.318
Cholesterol, VLDL-4, mg/dL	2.81 ± 1.83	3.77 ± 2.54	3.68 ± 2.20	2.72 ± 2.06	4.01 ± 3.14	3.41 ± 2.25	0.070	0.519	−0.500, 1.54	0.310
Cholesterol, VLDL-5, mg/dL	1.79 ± 0.44	2.43 ± 0.68	2.31 ± 0.52	1.84 ± 0.52	2.60 ± 0.84	2.63 ± 0.56	<0.001	0.641	0.394, 0.889	<0.001
Free cholesterol, VLDL-1, mg/dL	2.46 ± 1.56	1.93 ± 1.52	2.09 ± 1.74	0.93 ± 0.80	1.79 ± 1.41	1.61 ± 0.75	0.138	0.734	0.297, 1.17	0.002
Free cholesterol, VLDL-2, mg/dL	0.91 ± 0.64	0.83 ± 0.82	0.86 ± 0.84	0.48 ± 0.38	0.80 ± 0.89	0.62 ± 0.42	0.663	0.159	−0.027, 0.346	0.092
Free cholesterol, VLDL-3, mg/dL	0.94 ± 0.77	0.87 ± 0.94	0.89 ± 0.94	0.47 ± 0.52	0.85 ± 1.08	0.60 ± 0.52	0.695	0.146	−0.095, 0.388	0.228
Free cholesterol, VLDL-4, mg/dL	1.25 ± 0.74	1.62 ± 1.12	1.56 ± 0.98	1.19 ± 0.89	1.69 ± 1.36	1.48 ± 0.98	0.113	0.218	−0.240, 0.676	0.342
Free cholesterol, VLDL-5, mg/dL	0.64 ± 0.29	0.96 ± 0.40	0.89 ± 0.33	0.43 ± 0.28	1.07 ± 0.52	1.08 ± 0.33	<0.001	0.565	0.408, 0.722	<0.001
Phospholipids, VLDL-1, mg/dL	5.67 ± 3.54	4.17 ± 3.38	4.64 ± 3.89	3.06 ± 1.83	3.79 ± 3.24	3.29 ± 1.45	0.059	0.447	−0.413, 1.31	0.300
Phospholipids, VLDL-2, mg/dL	2.33 ± 1.41	1.93 ± 1.74	2.04 ± 1.88	1.63 ± 0.89	1.83 ± 1.88	1.41 ± 0.89	0.281	−0.164	−0.605, 0.277	0.457
Phospholipids, VLDL-3, mg/dL	2.35 ± 1.49	2.16 ± 1.92	2.19 ± 1.92	1.63 ± 1.17	2.13 ± 2.20	1.60 ± 1.22	0.636	−0.010	−0.576, 0.556	0.972
Phospholipids, VLDL-4, mg/dL	3.05 ± 1.27	3.82 ± 1.92	3.77 ± 1.59	3.33 ± 1.59	3.94 ± 2.44	3.63 ± 1.69	0.053	0.223	−0.544, 0.99	0.561
Phospholipids, VLDL-5, mg/dL	2.07 ± 0.45	2.69 ± 0.75	2.58 ± 0.61	2.28 ± 0.61	2.85 ± 0.94	2.87 ± 0.66	<0.001	0.434	0.175, 0.693	0.002

¹Values are mean ± SD unless otherwise indicated.