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. 2022 May 26;26(13):3726–3735. doi: 10.1111/jcmm.17401

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© 2022 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Recovery of blood flow, and therapeutic effects promoted by cell injection in a hind limb ischaemia model. (A) Representative laser doppler images of blood perfusion recovery in ischaemic hind limbs after cell transplantation. (B) Quantitative analysis of blood perfusion ratios. AMM/S injection improved blood flow compared with AMM treated mice 1 week after cell injection. **p < 0.01, *p < 0.05; n = 7 per group. (C) Representative images of salvaged limbs after AMM/S injection. (D) Quantitative analysis of limb salvage ratios