Figure 1:

(a) MESI system schematic with 2× magnification: A (Standard Iris, ID15, Thorlabs, Inc.), M (Ø1” Broadband Dielectric Mirror, BB1-E02, Thorlabs, Inc.), L1 (f = 50 mm, Steinheil Triplet Achromatic, 67–422, Edmund Optics, Inc.), F (685 ± 20 nm bandpass filter, S685/40m, Chroma Technology Corp.), and L2 (f = 100 mm, Achromatic Doublet, AC254–100-A, Thorlabs, Inc.). (b) Single exposure LSCI (5 ms) and MESI during the awake and anesthetized states in Subject 1 (Scale bar = 1 mm). See Video 1 (MPEG-4, 29.8 MB) for the transition between each state during the induction of general anesthesia.