Table 2. Summary of results of meta-analyses.
| Test | No. Studies Included | Total Sample Size (Range) | Sensitivity (95% CI): range reported in included studies | Sensitivity Meta-estimate (95% CI) | Specificity (95% CI): range reported in included studies | Specificity Meta-estimate (95% CI) | Area Under Curve (AUC) estimate |
|---|---|---|---|---|---|---|---|
| Crystal VC–Direct Samples | 8 [10, 32, 34, 40, 45, 47, 50, 56] | 7243 (76–5865) | 65.6 (52.7–77.1) to 100.0 (82.4–100.0) | 93.3 (83.7–97.5) | 60.0 (53.3–66.5) to 91.8 (81.9–97.3) | 77.7 (70.7–83.3) | 0.865 |
| Crystal VC–Enriched Samples | 5 [10, 24, 30, 32, 40] | 1614 (100–673) | 68.3 (51.9–81.9) to 98.9 (94.1–100.0) | 85.5 (68.1–94.4) | 90.0 (55.5–99.7) to 100.0 (94.4–100.0) | 98.3 (92.8–99.6) | 0.848 |
| Cholera Screen–Direct Samples | 31 [25, 29, 39] | 250 (17–99) | 98.0 (93.3–100.0) to 100.0 (69.2–100.0) | 98.6 (94.7–99.7) | 22.2 (6.4–47.6) to 100.0 (93.3–100.0) | 78.1 (18.9–98.2) | 0.966 |
| IP dipstick–Direct Samples | 22 [49, 59] | 414 (102–172) | 93.1 (84.5–97.7) to 98.5 (91.8–100.0) | 95.3 (91.1–97.5) | 77.0 (67.5–84.8) to 95.9 (88.6–99.2) | 87.4 (73.6–94.5) | 0.969 |
1One study undertaken in 2 separate locations so 4 results included
2One study undertaken in 2 separate locations so 3 results included