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. 2022 Jun 22;13:858881. doi: 10.3389/fphar.2022.858881

FIGURE 2.

FIGURE 2

YQHG improves renal function and fibrosis in 5/6 nephrectomized rats. (A) Experimental design. (B) The body weight of the rats was measured. (C) The kidney of the rats was photographed. (D–F) Effects of YQHG treatment on levels of Scr, BUN, and urinary protein in 5/6 nephrectomized rats. (G) Representative images of H&E (40 × Magnification, Scale bar 20 μm) staining and Masson (40 × Magnification, scale bar 20 μm) staining of renal tissues. (H–I) Quantitative analysis of glomerular fibrosis area and tubulointerstital fibrosis area based on Masson staining. All data are expressed as means ± SEM. For normally distributed data (body weight, Scr, BUN, urinary protein, glomerular fibrosis area, tubulointerstital fibrosis area), one-way ANOVA followed by Tukey’s test was used. *p < 0.05, **p < 0.01 vs. the sham group; # p < 0.05, ## p < 0.01 vs. the model group.