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. 2022 Jul 6;12(9):3456–3474. doi: 10.1016/j.apsb.2022.07.002

Figure 2.

Figure 2

Common features of type I and II mucosa and barriers for mucosal delivery. (A) Type I and type II mucosae are distributed in different tissues. There is a significant difference in the structural composition of the two, mainly in that the type I mucosa is composed of columnar epithelia, goblet cells, and M cells. It contains MALT and can secrete IgG and IgA. In contrast, the type II mucosa, which is composed of stratified squamous epithelium, does not have M cells, goblet cells or MALTs and cannot secrete IgA. (B) Common and special barriers limiting mucosal delivery.