Table 1.

Licensed mucosal vaccines.

Type of vaccine	Name	Antigen	Formulation	Disease	Administration	Approved time	Approved
Live attenuated122	OPV (b/m/tOPv)	Poliovirus	Aqueous	Poliomyelitis123	Oral	1961	FDA
Subunit vaccine	Dukoral®	Vibrio cholerae124 rCTB	Aqueous	Cholera	Oral	2003	Canada
Live attenuated	Fluenz™/FluMist®125	lnfluenza A and influenza B viruses	Spray	Influenza	Nasal	2003	FDA
Live reassortant126	RotaTeq®	Rotavirus	Aqueous	Infant diarrhea	Oral	2006	FDA
Live attenuated	Rotarix	RIX4414 strain127	Aqueous	Infant diarrhea	Oral	2008	FDA
Inactivated	Euvichol128 Shanchol	Vibrio cholerae	Aqueous	Cholera	Oral	2013	WHO
Live attenuated	Vivotif®129	Salmonella typhimurium	Capsule	Acute gastroenteritis	Oral	2013	FDA
Adenovirus vector vaccine130	Adenovirus Type 4 and Type 7 Vaccine	Adenovirus Type 4 and Type 7	/	Febrile acute respiratory disease	Oral	2011	FDA
Live attenuated	Vaxchora™	Vibrio cholerae131	Aqueous	Cholera	Oral	2015	FDA