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. 2022 Jul 6;68:25–36. doi: 10.1016/j.cytogfr.2022.07.002

Fig. 2.

Fig. 2

Therapeutic activity of mesenchymal stromal cells (MSCs). The MSC-mediated immunomodulation is mainly driven by direct cell-cell contacts as well as by soluble factors and extracellular vesicles (EVs) they release. List of abbreviations: NETs – Neutrophil Extracellular Traps; NK – Natural Killer; DCs – Dendritic Cells; IL-2 – Interleukin 2; IL-2R – Interleukin-2 receptor; PD-1 – Programmed cell death protein 1; PD-L1 – Programmed Death Ligand-1.