Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 2;17:2893–2905. doi: 10.2147/IJN.S363990

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 Chen et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Investigation of buffer-formulated mRNA-LNP3 complex transfection effect. (A) Comparison of different solutions as formulated buffers for mediating mRNA-LNP3 transfection to HEK293T cells. (B) Optimization and development of different formulated buffers based on SPMCG to explore the transfection effect of mRNA-LNP3 complex. The fluorescent images were collected from three time points after transfection, 24, 48 and 72 h. The scale bar was 100 μm.

Abbreviations: NS, normal saline; SB, sodium bicarbonate solution; RL, ringer lactate solution; PBS, phosphate buffer solution; SPMCG, sodium potassium magnesium calcium and glucose solution.