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Sequence alignment of Mpros from SARS-CoV-2, SARS-CoV, MERS-CoV and HCoV-NL63. Amino acid sequence of Mpros from SARS-CoV-2, SARS-CoV, MERS-CoV and HCoV-NL63 are retrieved from GenBank. ClustalX (1.83) software is used for sequence alignment and ESPript 3.0 was used to generate a graphical representation. The key residues involve in interacting with inhibitors are labeled with blue triangle.
