Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Association of TMB with APC mutations (A) APC mutation prevalence binned on the basis of sample TMB (orange line). Predicted monoallelic (red) and biallelic (blue) mutation prevalence was plotted on the same axes. (B) Fraction of APC mutations predicted as monoallelic (red) and biallelic (blue) in each TMB bin; analyses were limited to samples where allelic status could be determined. TMB, tumor mutational burden.
