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. 2022 May 4;43(26):2511–2522. doi: 10.1093/eurheartj/ehac207

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© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Structured Graphical Abstract — Patients presenting with breathlessness underwent TTE, CMR, and RHC. Cardiovascular magnetic resonance-modelled PCWP and TTE-estimated PCWP were both compared with invasively measured PCWP. The diagnostic accuracy of our CMR model was 71% compared with 25% for TTE. In cases where TTE was non-diagnostic (indeterminate or incorrect diagnosis), CMR correctly reclassified the correct diagnosis in 71%. Furthermore, CMR-derived PCWP was an independent predictor of survival. CMR, cardiac magnetic resonance; HF, heart failure; PCWP, pulmonary capillary wedge pressure; SOB, shortness of breath; TTE, transthoracic echocardiography; RHC, right heart catheterization.