Table 2.
MCCB scores and TGF-β1 levels
| Characteristic | Patients with schizophrenia* | Healthy controls* | t or χ2 | p value |
|---|---|---|---|---|
| MCCB domain score | ||||
| Speed of processing | 42.86 ± 13.06 | 59.00 ± 6.93 | −8.36 | < 0.001 |
| Attention/vigilance | 39.19 ± 13.33 | 58.05 ± 11.58 | −7.33 | < 0.001 |
| Working memory | 46.65 ± 10.94 | 58.62 ± 5.48 | −7.50 | < 0.001 |
| Verbal learning and memory | 46.74 ± 14.06 | 55.76 ± 7.36 | −4.36 | < 0.001 |
| Visual learning and memory | 44.20 ± 12.47 | 56.21 ± 6.17 | −6.66 | < 0.001 |
| Reasoning and problem solving | 46.14 ± 12.92 | 57.84 ± 5.04 | −6.66 | < 0.001 |
| Social cognition | 44.55 ± 13.44 | 54.47 ± 9.73 | −4.01 | < 0.001 |
| Composite score | 44.83 ± 9.86 | 59.83 ± 4.40 | −10.52 | < 0.001 |
| TGF-β1, μg/mL | 12.85 ± 6.01 | 8.46 ± 5.15 | 3.94 | < 0.001 |
MCCB = MATRICS Consensus Cognitive Battery; TGF-β1 = transforming growth factor-β1.
*
Data are mean ± standard deviation.