Fig. 5. NET formation in LPS-exposed lungs.
a Feature plot of PADI4 expression across hematopoietic cell populations of IA LPS-exposed fetuses. b PADI4 mRNA expression was analyzed by RT-PCR in the fetal lung of control animals compared to IA-LPS injection. c Representative immunofluorescence staining of NETs in IA-LPS-exposed fetal lung (60X, Insert: 100X); scale bar is 50 μm. d Average area of NET in the control and IA LPS fetal lungs. Each symbol represents one animal, with median and interquartile ranges displayed, Mann–Whitney U test; **p ≤ 0.01.