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. 2022 Jul 6;12:11447. doi: 10.1038/s41598-022-15572-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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STOML2 is expressed in ensheathing cells but not in olfactory sensory neuron axons. Confocal micrographs of coronal sections of the OB of WT (a–c), Triple KO (g-i), and Stoml3 KO (j-l) mice double-stained with anti-STOML2 (red) and anti-OMP (green) antibodies. In all three mice models, STOML2 has a uniform and strong expression in the external nerve layer of the OB while is weakly present in more internal layers including the glomeruli. (d-f) Higher magnification of OSN axon bundles shows the localization of STOML2 in ensheathing cells. Nuclei were stained with DAPI (blue).