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. 2022 Jul 6;13:3880. doi: 10.1038/s41467-022-31564-1

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© The Author(s) 2022, corrected publication 2022

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Fig. 1 — a HMM vs. HMM homology probabilities of a subset of eukaryotic, viral, and archaeal fusexin ectodomains. With exception of Fsx1, which derives from a metagenomic sequence, archaeal fusexins (red), viral fusexins (blue), EFF-1 (green) and HAP2s (black) are indicated by RefSeq/UniProt identifiers. b Crystal structure of the trimeric ectodomain of Fsx1. The three-fold non-crystallographic axis is indicated. Subunit A is shown as a cartoon colored by domain, with disulfides and the fusion loop (FL) colored magenta and orange, respectively; subunits B, C are in mixed cartoon/surface representation.