Fig. 6. Environmental distribution of Fsx1s.
a Archaeal fusexins unrooted phylogeny, environmental details, and trimeric models66 based on the Fsx1 X-ray structure (PDB 7P4L [https://www.rcsb.org/structure/7P4L], enlarged). Tree tip IDs coming from metagenomic data coded by sampling site, sample id and sequence (see Supplementary Data 1). Fsx1s from cultivated genomes are shown as Natrialbales and Haloferacales orders in blue and red, respectively. Surfaces colored and oriented as in Fig. 3a. Found in diverse environments and often differing in global surface properties, modeled trimers share hydrophobic tips. b Panel with phylogenomic tree for fsx1-containing cultured archaeal species, showing incongruences between Fsx1s in Haloferacales.