Table 2.

Non-pathogenic CNVs in 1kGP and AMP-PD cohorts.

	1kGP			PD						LBD
	European	African	Other	European		African		Other or unknown		European
	Control	Control	Control	Case	Control	Case	Control	Case	Control	Case	Control
CNL	2	3	9	8a	7	0	0	0	0	13c	13
CNG	1	74	18	11b	6	1	2	0	1	21d	11e
Total	503	661	1340	2227	1213	22	27	76	15	2598	1941

^aThree out of the eight PD cases with non-pathogenic CN losses also have a pathogenic GBA variant (two samples have p.L483P and one sample has p.N409S).

^bFour out of the 11 PD cases with CN gains also have a pathogenic GBA variant (three samples have p.L483P and one sample has p.N409S).

^cOne out of the 13 LBD cases with non-pathogenic CN losses also has a pathogenic GBA variant, p.L483P.

^dFive out of the 21 LBD cases with CN gains also have a pathogenic or PD-related GBA variant (p.L483P, p.D448H, c.1263del+RecTL, p.T408M, and compound heterozygote p.L483P/p.D448H).

^eOne out of 11 LBD controls with CN gains also has a PD-related GBA variant, p.T408M.