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. 2022 Jun 23;13:898493. doi: 10.3389/fimmu.2022.898493

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Copyright © 2022 Yi, Zheng, Xu, Li, Zhang, Ge, Liao, Li, Lyu and Ai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IGFBP7 predicts the molecular subtype and the therapeutic response to several therapies in BLCA. (A) Correlations between IGFBP7 and molecular subtypes using different algorithms and bladder cancer signatures. (B) The enrichment scores of 12 molecular subtype-specific signature in the high- and low-IGFBP7 groups. (C, D) Correlations between IGFBP7 and the enrichment scores of several therapeutic signatures. (E) Correlation between IGFBP7 and the BLCA-related drug-target genes obtained from the Drugbank database. *p< 0.05; **p<0.01; ***p<0.001. ns, no significance; ns, p≥0.05.