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. 2022 Jun 23;13:898493. doi: 10.3389/fimmu.2022.898493

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Copyright © 2022 Yi, Zheng, Xu, Li, Zhang, Ge, Liao, Li, Lyu and Ai

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Development of IGFBP7-based immune risk model. (A) Venn diagram showing the candidate gene set. (B) Forest plot of the correlation between the candidate genes and prognosis in BLCA. (C, D) Kaplan-Meier survival curve analysis of the low- and high-risk in TCGA training set and the predictive accuracy of risk model for survival. (E–I) Validation of the risk model in five external independent sets: GSE13507, GSE31684, GSE32894, GSE48277, IMvigor210. (J, K) Correlations between riskscore, expression of IGFBP7 and pan-cancer T cell inflamed score.