Table 3.
Results of univariate and multivariate logistic regression analysis assessing the determinants of pituitary hormone deficiency at study entry in subjects with empty sella.
| UNIVARIATE ANALYSIS | MULTIVARIATE ANALYSIS | ||||||
|---|---|---|---|---|---|---|---|
| Covariates | N. cases | OR | 95% C.I. | P-values | OR | 95% C.I. | P-values |
| Age | 402 | 1.00 | 0.99-1.01 | 0.882 | |||
| Male sex | 402 | 2.71 | 1.78-4.12 | < 0.001 | 2.05 | 1.12-3.73 | 0.019 |
| BMI | 379 | 0.99 | 0.97-1.03 | 0.830 | |||
| Clinical suspicion | 402 | 6.02 | 3.73-9.71 | < 0.001 | 4.27 | 2.19-8.34 | < 0.001 |
| Traumatic brain injury | 221 | 2.25 | 1.19-4.26 | 0.013 | 2.80 | 1.41-5.57 | 0.003 |
| N. of pregnancies | 229 | 1.04 | 0.86-1.26 | 0.685 | |||
| Entity of ES | 321 | 1.46 | 0.81-2.62 | 0.211 | |||
BMI, body mass index; C.I., confidence interval; ES, empty sella; OR, odds ratio.