Table 5.
Comparison of the ICSI outcomes of NOA patients with different sperm quantity.
| Lower sperm count(n =64) | Higher sperm count(n =235) | P-value | |
|---|---|---|---|
| Male’s age (y) | 31.11 ± 4.56 | 31.63 ± 4.83 | 0.444 |
| Female’s age (y) | 28.97 ± 4.30 | 29.14 ± 3.99 | 0.770 |
| Male’s FSH (IU/L) | 21.89 ± 12.62 | 18.75 ± 10.29 | 0.041* |
| No. of MII oocytes for ICSI | 15.09 ± 6.76 | 14.19 ± 7.37 | 0.376 |
| No. of available embryos on day3 | 2.14 ± 1.92 | 3.37 ± 2.94 | 0.002* |
| No. of high-score embryos on day 3 | 0.58 ± 0.87 | 0.94 ± 1.19 | 0.025* |
| Day 3 utilization rate of MII eggs for ICSI %1 | 9.67 ± 5.05 | 11.31 ± 8.58 | 0.145 |
| Rate of high-score embryo on day 3%2 | 9.5 (37/390) | 13.5 (220/1625) | 0.031* |
| No. of partial oocytes freezing cycles/OPU cycles (%) | 23.4 (15/64) | 11.9 (28/235) | 0.020* |
| No. of patients without available embryos/ICSI cycles (%) | 25.0 (16/64) | 8.1 (19/235) | 0.000* |
| Pregnancy | |||
| No. of patients with clinical pregnancy/undergoing ICSI cycles with available embryos (%) | 39.6 (19/48) | 60.6 (131/216) | 0.008* |
| No. of patients with clinical pregnancy/undergoing ICSI cycles (%) | 29.7 (19/64) | 55.7 (131/235) | 0.000* |
| No. of patients with clinical pregnancy/successful sperm retrieval (%) | 19.0 (24/126) | 52.9 (162/306) | 0.000* |
| Live birth | |||
| No. live birth/clinical pregnancy (%) | 94.7 (18/19) | 93.1 (122/131) | 0.793 |
| Singleton (%) | 100.0 (18/18) | 85.2 (104/122) | 0.081 |
| Twins (%) | 0 (0/18) | 14.8 (18/122) | |
| No. live birth/undergoing ICSI cycles with available embryos (%) | 37.5 (18/48) | 56.5 (122/216) | 0.017* |
| No. live birth/undergoing ICSI cycles (%) | 28.1 (18/64) | 51.9 (122/235) | 0.001* |
| No. live birth/successful sperm retrieval (%) | 17.5 (22/126) | 48.7 (149/306) | 0.000* |
| No. premature infants/live birth (%) | 5.6 (1/18) | 22.1 (27/122) | 0.101 |
| No. cesarean delivery/live birth (%) | 22.2 (4/18) | 32.8 (40/122) | 0.367 |
| No. birth defects/live birth (%) | 5.6 (1/18) | 0.8 (1/122) | 0.114 |
| Gender | / | / | 0.974 |
| Male (%) | 38.9(7/18) | 39.3(55/140) | / |
| Female (%) | 61.1(11/18) | 60.7(85/140) | / |
| Birth weight (g) | / | / | / |
| Singleton (n =122) | 3073.33 ± 461.11 | 3191.63 ± 411.33 | 0.271 |
| Twins (n =18, 36 babies) | 0 | 2327.50 ± 324.95 | / |
| Height (cm) | / | / | / |
| Singleton (n =122) | 48.94 ± 2.82 | 49.79 ± 2.10 | 0.139 |
| Twins (n =18, 36 babies) | 0 | 45.19 ± 3.32 | / |
Data are expressed as mean ± SD unless indicated otherwise; 1 and 2, the definitions see Table 1 .
* Significantly different.