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. 2022 Jun 23;10:940634. doi: 10.3389/fbioe.2022.940634

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Copyright © 2022 Guo, Zhu, Gao, Chen, Lu, Yan, Liu, Wang, Ding, Huang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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IHC detection of ALB, CYP3A4, and MRP₂ expression in both groups after transplantation. Protein expressions increased gradually over time. Compared with monocultures, the co-culture group showed upregulated expressions at each time point. Scale bar, 50 µm.