TABLE 1.

PLGA-MPs acceptance criteria.

Test	Acceptance criteria
Appearance	Clear, colorless solution, practically free from particulate matter
PSD (Particle size distribution)	3 µm ≤ PSD (0.5) ≤ 9 µm
Morphology by SEM	Smooth-surface spherical particles
rhNGF efficiency of encapsulation (%) by ELISA	˃50%
rhNGF release (mg/ml)	Controlled release (≥50 days)
Potency (TF-1 proliferation bioassay)	70%–130% of reference material