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. 2022 Jun 23;9:759928. doi: 10.3389/fmed.2022.759928

FIGURE 3.

FIGURE 3

The functions of nuclear and cytoplasmic circRNAs. (A) ecircRNA’s effect of transcriptional pausing. (B) EIciRNA binds with Pol II and U1 snRNP to promote transcription. (C) circRNA in cytoplasm serves as miRNA sponge. (D) circRNA presents as translation template to produce protein. (E) Cytoplasmic ecircRNA acts as “scaffolding” for RBPs.