TABLE 3.

Effect of compound 6d on 3-mercaptopropionic acid-induced seizures in mice.

Compound	Dose (mg/kg)	Test time (h)	Clonic seizure (%)	Tonic seizure (%)	Lethality (%)
DMSO	—	0.5	100	100	70
Carbamazepine	30	0.5	100	0***	0**
6d	30	0.5	0***	0***	0**

Results are expressed as the percentage of animals showing clonic and tonic convulsions and death in all animals tested. Ten mice were included in each group. Significance was determined with Fisher’s exact test. **p < 0.01 and ***p < 0.001 vs. group of 3-MP (60 mg/kg).