TABLE 7.

Mean number of injections at 1-year follow-up.

Mean number of injections of included studies in the below outcomes	Mean number of injections
	IVT-AFL	IVR	IVC*
BCVA mean change from baseline (measured by ETDRS letters)	7.52	7.77	9.5
The proportion of patients with a gain of at least 15 ETDRS letters	8.88	8.93	9.5

Bi-monthly or PRN (pro re nata) regimens were used in included trials. *Data was identified from only one RCT (Liu 2021, conbercept PRN).

BCVA, best-corrected visual acuity; ETDRS, early treatment diabetic retinopathy study; IVC, intravitreal conbercept; IVR, intravitreal ranibizumab; IVT-AFL, intravitreal aflibercept.