Figure 6.

Effect of co-treatment of zinc compounds and known anti-HEV compounds on g3-HEV replication. (A) Measurement of G-Luc activity in Huh7 cells expressing in vitro synthesized capped RNA of a g3-HEV-Luc replicon and treated for 3 days (once daily) with the indicated concentration of different compounds. G-Luc values were normalized to that of the cell viability and represented as mean ± SEM. (B) Measurement of G-Luc activity in Huh7 cells expressing in vitro synthesized capped RNA of a g3-HEV-Luc replicon and treated for 24 h with the indicated concentration of different compounds. G-Luc values were normalized to that of the cell viability and represented as mean ± SEM of three independent experiments.