Fig. 6.

This figure depicts the compounds, and a selection of RXNs and genes that are included in the phenylpropanoid biosynthesis pathway in P. trichocarpa. This figure also depicts the genes that are recovered by GENIE3 and iRF-LOOP in the EC 6.2.1.12 and EC 2.3.1.133 RXNs within the phenylpropanoid biosynthesis pathway. For comparison, in this figure the GENIE3 PEN is thresholded to match the same network size as the PEN created by iRF-LOOP. A) The entire phenylpropanoid pathway in P. trichocarpa is shown with the two RXNs of interest shown in blue. B) All of the theoretically possible edges between the known genes associated with the two RXNs. C) The genes and edges recovered by iRF-LOOP. D) The genes and edges recovered by GENIE3.