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. 2022 Jun 25;9:101774. doi: 10.1016/j.mex.2022.101774

Table 1.

Validation parameters for the methodology used to quantify HMF and FF.

Analyte Linear range (mmol L−1) Equation of the line R2 LOD
(mmol L−1)
LOQ
(mmol L−1)
Level
(mmol L−1)
Rep. RSD(%) n = 10 Int. prec. RSD(%) n=10 Rec. RSD(%) n = 3
HMF 3.00 × 10−2 2.10 × 10−1 y = (x-0.5562)/
50.2139
0.9972 0.002371 0.035249 0.048 0.83 2.89 98.76
0.120 0.84 3.97 98.63
0.192 3.90 3.34 97.26
FF 5.00 × 10−4 3.00 × 10−2 y = (x-0.0011)/ 50.5597 0.9998 0.000855 0.012651 0.0035 0.72 0.41 97.80
0.0153 1.23 1.63 94.56
0.0271 4.46 5.87 91.12

R2 = coefficient of determination; LOD = limit of detection; LOQ = limit of quantification; RSD = relative standard deviation; Rep. = repeatability; Int. prec. = intermediate precision; Rec. = recovery.