Table 2.

Summary of the few significant oral virome in healthy and infectious conditions.

Model	Sample	Type of infection	Study type	Findings	References
Children	Saliva	Food and Mouth Diseases, Mouth ulcer	Young children (n = 55)	Bacteriophages (n = 27, 67.5%) vertebrate viruses (n = 11, 27.5%) and plant viruses (n = 2, 5%)	[30]
Human	Saliva, Sub gingival & Supragingival plaque, Control (healthy adults)	Periodontal diseases and healthy mouth	n = 16 (Chronic severe generalized periodontitis (n = 7) and good periodontal health n = 9).	Siphoviridae Myoviruses Podoviridae	[100]
Young adults	Oral rinse	Healthy individuals	Young adults (n = 72)	Bacteriophages (Siphoviridae and Myoviridae, and Streptococcus phages) Viral (Herpes viridae) Caudovirales, Siphoviridae (71 samples) and Myoviridae (68 samples), Streptococcus phages (up to 69 samples), Eukaryotic viruses (Herpes viridae family (65 samples), Human herpes virus 7 (from 61 samples out of the 72 samples)	[17]
Volunteer’s	Salivary sample	good overall periodontal health individuals	n = 15	Prophage (Streptococcus phages), Caudovirales	[28]
Oral cavity Patients	Oral rinse	Patients admitted in the hospital with oral cavity diseases	n = 124 patients (Male: n = 48 Female: n = 76)	Human papilloma virus (HPV)16 – Male: N-38 and Female: N-56	[109]
Infants	Oral swab	HIV infected women and Non HIV infected women	n = 32	Identified: Cytomegalovirus	[110]