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. 2022 Jul 2;58:208–216. doi: 10.1016/j.jdsr.2022.06.002

Table 1.

Classification of HPP.

Types Period of diagnosis Major symptoms Inheritance patterns
Perinatal Fetal to neonatal Severe bone hypomineralization
Respiratory disorder
Convulsions
Autosomal recessive
Prenatal benign Bowed long bones Autosomal recessive or autosomal dominant
Infantile < 6 months of age Failure to thrive
Hypercalcemia
Premature craniosynostosis
Autosomal recessive
Childhood 6 months to 18 years old Early exfoliation of primary teeth
Short stature
Bone pain
Autosomal recessive or autosomal dominant
Adult ≥ 18 years of age Fracture
Periodontitis
Autosomal recessive or autosomal dominant
Odonto Regardless of age Early exfoliation of primary teeth
Periodontitis
Autosomal recessive or autosomal dominant