Table 2.
Common delivery systems for bioactives.
| Delivery system | Benefits | Potential applications | References |
|---|---|---|---|
| Liposome | Sustained and targeted drug delivery; reducing drug-induced toxicity; improving drug solubility; increasing circulation time; overcoming multi-compound resistance; and improving the therapeutic index | Agrochemical; pharmaceutical; cosmetic; and food industries | (Shishir et al., 2019) |
| Micro and nanoencapsulation | Production of stable capsules; protection of the core compound from moisture, oxygen, and UV rays; allows the modification and/or improvement of the properties of the active substance; increase the shelf life of a volatile compound; control release; reduces agglomeration of fine powders; improve the handling properties of sticky materials, and prevent chemical reactions with external factors | Agrochemical; cosmetic, food; pharmaceutical; and textile industries | (Ribeiro et al., 2020) |
| Nanoemulsion, nanoparticles, phytosomes, nanovesicles, nanoliposomes, and niosomes | Enhanced penetrability and bioavailability of the active compounds; penetration to the cell membranes; encapsulating both hydrophilic and hydrophobic drugs; slowing the rate of drug break down, extending the drug half-life, stabilizing sensitive drugs, lessening the toxic and side effects of drugs; improving entrapment efficiency | Cosmetics; agrochemical; food; and pharmaceutical industries | (Karimi et al., 2017) |
| Bilosomes and Double emulsions (duplex or multiple emulsions) | Easy availability and high potency as penetration enhancers to improve the oral bioavailability, co-delivery of nutraceuticals, fat and salt reduction e in foods without altering the food's native sensory properties | Agrochemical; food; cosmetics and pharmaceutical industries | (Aditya et al., 2017) |
| Polymeric and inorganic nanoparticles, Protein-based nanocarriers, Lipid-based and vesicular delivery systems, and exosomes |
Improved drug bioactivity, low toxicity, the capability of evading the immune system, ability to cross the permeability barrier of the skin, enhanced drug penetration into and through the skin |
Agrochemical; food; cosmetics and pharmaceutical industries | (Lagoa et al., 2020) |