Figure 3.

Virtual sensor time series indicate group differences in oscillatory responses. (A) Relative amplitude time series from the peak voxel across all participants showing neural responses to the stimulation in each group. The colour legend appears on the bottom of the figure. As shown, persons with Alzheimer’s disease exhibited much stronger oscillatory responses to each stimulation compared with both controls and those with HAND. Grand average beamformer images shown above time series reflect location of peak voxel. (B) Bar graph of the mean relative amplitude of neural responses to Stimulation 1 at the peak voxel. Data have been averaged over the time window used for beamformer image computation (i.e. 0–50 ms) per participant and then group. Responses were much stronger in those with Alzheimer’s disease. (C) Same as B except that the data reflect responses to Stimulation 2 (i.e. 500–550 ms). ANOVA models (group × stimulation) were computed, and these indicated significant group differences. Follow-up post hoc analyses were conducted. *P < .05; ^#P = 0.054.