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. 2022 Jun 30;4(4):fcac171. doi: 10.1093/braincomms/fcac171

Figure 4.

Figure 4

VitD modulates different cellular and molecular mechanisms of CNS-resident cells and of the blood–brain barrier involved in multiple sclerosis pathology. (Left) Schematic representation of the cellular and molecular mechanisms involved in multiple sclerosis/EAE pathology at the level of CNS-resident cells and the BBB. (Right) Schematic representation VitD impact on cellular and molecular mechanisms involved in multiple sclerosis/EAE pathology at the level of CNS-resident cells and the BBB. Changes in the cellular and molecular mechanisms are given as (↑) increased and (↓) decreased. Drawings of the individual cell types were adapted from Servier Medical Art (http://smart.servier.com/), licenced under a Creative Common Attribution 3.0 Generic License.