Table 1. Baseline demographic and clinical characteristics of critically ill cirrhotics.
| Variable | All (n=111) (%) | Sarcopenic (n=76) (%) | Non-sarcopenic (n=35) (%) | P-value |
|---|---|---|---|---|
| Age (years) | 48.37±11.29 | 48.49±11.5 | 48.11±10.9 | 0.873 |
| Gender | ||||
| Male | 92 (83.8) | 65 (85.5) | 28 (80) | 0.463 |
| Female | 18 (16) | 11 (14.5) | 7 (20) | |
| Diagnosis | ||||
| CLD | 92 (82.9) | 60 (78.9) | 32 (91.4) | 0.105 |
| ACLF | 19 (17.1) | 16 (21.1) | 3 (8.6) | |
| Etiology | ||||
| Ethanol | 56 (50.5) | 40 (52.6) | 16 (45.7) | 0.094 |
| NASH | 27 (24.3) | 14 (18.4) | 13 (37.1) | |
| Viral | 12 (10.8) | 8 (10.5) | 4 (11.4) | |
| Others | 16 (14.4) | 14 (18.4) | 2 (5.7) | |
| Comorbidities | 51 (45.9) | 34 (44.7) | 17 (48.6) | 0.706 |
| Reason for admission | ||||
| Hepatic encephalopathy | 67 (60.4) | 45 (59.2) | 22 (62.9) | 0.715 |
| Variceal bleed | 14 (12.6) | 7 (9.2) | 7 (20) | 0.112 |
| Respiratory distress | 33 (29.7) | 21 (27.6) | 12 (34.5) | 0.476 |
| Shock | 22 (19.8) | 16 (21.1) | 6 (17.1) | 0.631 |
| Others | 16 (14.4) | 11 (14.5) | 5 (14.3) | 0.979 |
| Presence of ascites | 68 (61.3) | 46 (60.5) | 22 (64.7) | 0.677 |
| Dry BMI (kg/m2) | 24±4.32 | 22.9±3.7 | 26.3±4.6 | <0.001* |
| SMD | 51.82±9.77 | 50.58±10.22 | 54.52±8.22 | 0.033* |
| CTP score | 11.94±1.83 | 11.8±1.8 | 12.06±1.8 | 0.642 |
| Child B | 8 (7.2) | 7 (9.2) | 1 (2.9) | 0.229 |
| C | 103 (92.3) | 69 (90.8) | 34 (97.1) | |
| MELD score | 27.87±7.35 | 28.2±8.2 | 27.6±7.7 | 0.690 |
| SOFA score | 10.52±4.11 | 10.6±3.9 | 10.1±4.5 | 0.545 |
| APACHE II score | 23.04±8.03 | 23.6±7.9 | 21.6±8 | 0.231 |
| Sepsis at baseline | 52 (46.8) | 41 (53.9) | 11 (31.4) | 0.027* |
| Presence of AKI | 59 (53.1) | 43 (56.8) | 16 (45.7) | 0.286 |
| Requirement of RRT | 13 (22) | 9 (11.8) | 4 (11.4) | 0.950 |
Data are expressed as Mean±SD or number (%),
*
significant at P<0.05; CLD: Chronic liver disease; ACLF: Acute-on-chronic liver failure; NASH: Non-alcoholic steatohepatitis; BMI: Body mass index; SMD: Skeletal muscle density; CTP: Child-Turcotte-Pugh; MELD: Model for end-stage liver disease; SOFA: Sequential Organ Failure Assessment; APACHE II: Acute Physiology, Age, Chronic Health Evaluation II; AKI: Acute kidney injury; RRT: Renal replacement therapy