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. 2022 Jun 23;9:910291. doi: 10.3389/fnut.2022.910291

Table 4.

Interaction of hydration status and physical activity level on renal damage using generalized linear mixed–effects models among 6–9–year–old children in Beijing (N = 1914).

Dependent variables Independent variables Model 1 Model 2 Model 3
cOR (95%CI) P aOR (95%CI) P aOR (95%CI) P
Tubular Dehydration + Insufficient PA ref.
damage Dehydration + Sufficient PA 0.81 (0.65, 1.01) 0.066 0.82 (0.66, 1.02) 0.074 0.81 (0.65, 1.02) 0.069
Euhydration + Insufficient PA 0.47 (0.41, 0.55) <0.001 0.46 (0.39, 0.53) <0.001 0.46 (0.39, 0.53) <0.001
Euhydration + Sufficient PA 0.60 (0.46, 0.79) <0.001 0.58 (0.44, 0.76) <0.001 0.57 (0.44, 0.75) <0.001
Glomerular Dehydration + Insufficient PA ref.
damage Dehydration + Sufficient PA 0.93 (0.65, 1.33) 0.67 0.94 (0.65, 1.37) 0.76 0.95 (0.66, 1.38) 0.80
Euhydration + Insufficient PA 0.31 (0.22, 0.42) <0.001 0.28 (0.20, 0.38) <0.001 0.28 (0.20, 0.39) <0.001
Euhydration + Sufficient PA 0.52 (0.33, 0.80) 0.004 0.47 (0.30, 0.73) 0.001 0.47 (0.30, 0.74) 0.001

PA, physical activity; cOR, crude odds ratio; aOR, adjusted odds ratio; CI, confidence interval; ref., reference group; Model 1, unadjusted; model 2, adjusting for age, sex, and BMI z–score; model 3, adjusting for age, sex, BMI z–score, standardized SBP, sleep duration, screen time, and fruit and vegetable intake. All models included two random effects: the week–day and intra–wave of the urinalysis.