Table 2.

Dosing Decision Table for the BOIN-ET Design.

	0≤ ${\hat{p}}_j$ ≤ λe	λe < ${\hat{p}}_j$ ≤ λd	λd < ${\hat{p}}_j$ ≤ 1
${\eta }_1<{\hat{q}}_j\le 1$	Stay	Stay	De-escalate
$0\le {\hat{q}}_j$ ≤ η1	Escalate	Escalate/Stay/De-escalate	De-escalate