Table 4.

Decision Table (RDS Table) for BOIN12 assuming the upper toxicity limit ϕ_T to be 0.35 and the lower efficacy limit ϕ_E to be 0.25 and the utility specification given in Table 1 of Lin et al. [21].

No of Patients	No of Toxicities	No of Efficacies	Desirability Score
0	0	0	60
3	0	0	35
3	0	1	55
3	0	2	76
3	0	3	91
3	1	0	24
3	1	1	44
3	1	2	63
3	1	3	80
3	2	0	13
3	2	1	31
3	2	2	48
3	2	3	69
3	3	Any	ED
6	0	0	22
6	0	1	38
6	0	2	51
6	0	3	67
6	0	4	81
6	0	5	93
6	0	6	100
6	1	0	15
6	1	1	27
6	1	2	42
6	1	3	56
6	1	4	72
6	1	5	87
6	1	6	96
6	2	0	8
6	2	1	19
6	2	2	34
6	2	3	47
6	2	4	64
6	2	5	77
6	2	6	90
6	3	0	4
6	3	1	12
6	3	2	22
6	3	3	38
6	3	4	51
6	3	5	67
6	3	6	81
6	4	0	1
6	4	1	6
6	4	2	15
6	4	3	27
6	4	4	42
6	4	5	56
6	4	6	72
6	≥5	Any	ED

ED means the dose should be eliminated because it does not satisfy the safety and efficacy admissible criteria (i.e., not admissible because of high toxicity or low efficacy).