Skip to main content
. 2022 Jun 13;28:100943. doi: 10.1016/j.conctc.2022.100943

Table 6.

Desirability score table for the BOIN Comb design with the target DLT probability of 0.3 [1].

Number of Patients Number of DLTs Desirability Score
0 0 6
3 0 7
3 1 11
3 2 5
3 ≥3 E
6 0 3
6 1 13
6 2 16
6 3 10
6 ≥4 E
9 0 2
9 1 9
9 2 17
9 3 18
9 4 12
9 ≥5 E

“E”: eliminate current and higher doses.