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. 2022 Jul 6;5(7):e2219672. doi: 10.1001/jamanetworkopen.2022.19672

Table 1. Definitions of Dementia Risk Factors and Sources of Prevalence Estimates.

Risk factor Definition Source (year)
Less education Self-reported <12 y of schooling ACS (2014-2018)
Obesity Measured BMI ≥30 NHANES (2015-2018)
Hypertension Self-report of taking antihypertensive medications or measured SBP ≥140 mm Hg or measured DBP ≥90 mm Hg NHANES (2015-2018)
Diabetes Self-report of diagnosis or measured fasting plasma glucose ≥126 mg/dL or measured HbA1C ≥6.5% NHANES (2015-2018)
Hearing loss Pure-tone mean >25 dB hearing threshold in better ear measured at 0.5, 1, 2, and 4 kHz NHANES (2015-2016)
Smoking Self-report of current smoking NHIS (2014-2018)
Physical inactivity Self-report of not doing either 75 min/wk of vigorous activity or 150 min/wk of moderate activity or 150 min/wk of moderate/vigorous activity NHIS (2014-2018)
Excessive alcohol consumption Self-report of drinking more than 14 alcoholic drinks (eg, 12 oz of beer, 5 oz of wine, 1.5 oz of spirits) per wk NHIS (2014-2018)
Social isolation Self-report of contact with family, friends, religious organizations, organized groups, or volunteering less than once per mo NSHAP (2015-2016)
Traumatic brain injury Self-report of lifetime head injury resulting in loss of consciousness NHANES (2011-2014)
Depression PHQ-9 score ≥10 NHANES (2015-2018)
Air pollution NO2 concentration ≥8.7 ppb at census tract level CACES (2015)

Abbreviations: ACS, American Community Survey17; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CACES, Center for Air, Climate, and Energy Solutions21; NHANES, National Health and Nutrition Examination Survey18; NHIS, National Health Interview Survey19; NSHAP, National Social Life Health and Aging Project20; PHQ-9, Patient Health Questionnaire-9.